Characterization and optimization of liquid electrodes for lateral dielectrophoresis.

نویسندگان

  • Nicolas Demierre
  • Thomas Braschler
  • Pontus Linderholm
  • Urban Seger
  • Harald van Lintel
  • Philippe Renaud
چکیده

Using the concept of insulator-based "electrodeless" dielectrophoresis, we present a novel geometry for shaping electric fields to achieve lateral deviation of particles in liquid flows. The field is generated by lateral planar metal electrodes and is guided along access channels to the active area in the main channel. The equipotential surfaces at the apertures of the access channels behave as vertical "liquid" electrodes injecting the current into the main channel. The field between a pair of adjacent liquid electrodes generates the lateral dielectrophoretic force necessary for particle manipulation. We use this force for high-speed deviation of particles. By adding a second pair of liquid electrodes, we focus a particle stream. The position of the focused stream can be swept across the channel by adjusting the ratio of the voltages applied to the two pairs. Based on conformal mapping, we provide an analytical model for estimating the potential at the liquid electrodes and the field distribution in the main channel. We show that the simulated particle trajectories agree with observations. Finally, we show that the model can be used to optimize the device geometry in different applications.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

AC Electrophoresis; Deposition of Ceramic Nanaoparticles on In-plane Electrodes at Low Frequencies (RESEARCH NOTE)

Deposition of ceramic nanoparticles (dispersed in a non-aqueous suspension) on in-plane electrodes and under the influence of AC electric fields in the frequency range of 0.01 Hz - 10 kHz is investigated. Analysis of the particle response to the applied field is a difficult task due to the mutual effect of electric- and hydrodynamic force which are present in the system. In this work, however, ...

متن کامل

Microfluidic characterization and continuous separation of cells and particles using conducting poly(dimethyl siloxane) electrode induced alternating current-dielectrophoresis.

This paper presents a poly(dimethyl siloxane) (PDMS) polymer microfluidic device using alternating current (ac) dielectrophoresis (DEP) for separating live cells from interfering particles of similar sizes by their polarizabilities under continuous flow and for characterizing DEP behaviors of cells in stagnant flow. The ac-DEP force is generated by three-dimensional (3D) conducting PDMS composi...

متن کامل

Optimization of Liquid DiElectroPhoresis (LDEP) Digital Microfluidic Transduction for Biomedical Applications

Digital microfluidic has recently been under intensive study, as an effective method to carry out liquid manipulation in Lab-On-a-Chip (LOC) systems. Among droplet actuation forces, ElectroWetting on Dielectric (EWOD) and Liquid DiElectroPhoresis (LDEP) are powerful tools, used in many LOC platforms. Such digital microfluidic transductions do not require integration of complex mechanical compon...

متن کامل

Isolation of Single Dna Molecule in a Picolitre-sized Droplet Formed by Liquid Dielectrophoresis

This paper reports a novel method to isolate single DNA molecules in an open container filled with oil by using Liquid Dielectrophoresis (LDEP). We successfully demonstrated the formation of 12 droplets (~200pL) from a 0.5μL DNA solution parent droplet. The parent droplet is put on 2 parallel electrodes. When an AC voltage was applied between these electrodes, the droplet deforms in a finger ri...

متن کامل

A Concept of Moving Dielectrophoresis Electrodes Based on Microelectromechanical Systems (mems) Actuators

A concept of moving dielectrophoresis electrodes (MDEP) based on Microelectromechanical Systems (MEMS) actuators is introduced in this letter. An example design of tuneable dielectrophoresis filter is presented. Finite Element Analysis of the electrostatic field of the tuneable filter has been conducted. Results show that the trapping force can be adjusted by actuating the MEMS actuators. The p...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Lab on a chip

دوره 7 3  شماره 

صفحات  -

تاریخ انتشار 2007